Program
| Time |
Event |
|
|
08:00 - 08:30
|
Welcome and Registration - Welcome of participants and package distribution |
|
|
08:30 - 08:45
|
Few words of introduction |
|
|
08:45 - 10:45
|
SESSION 1: Genomes, gene expression, DNA replication (DIAPASON) - Gert Veenstra/Luc Paillard |
|
| 08:45 - 09:15 |
› Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 - Thomas Hollemann, University of Halle-Wittenberg |
|
| 09:15 - 09:45 |
› Timing is everything: revisiting zygotic genome activation through the lens of time-resolved gene expression profiles - Mike Gilchrist, The Francis Crick Institute |
|
| 09:45 - 10:15 |
› Glucocorticoid effects on thyroid hormone gene regulation in Xenopus tropicalis tadpoles - LAURENT SACHS, Evolution of endocrines regulations |
|
| 10:15 - 10:45 |
› Identification of cis-regulatory elements in Xenopus neural crest formation - Grant Wheeler, University of East Anglia |
|
|
10:45 - 11:05
|
Coffee break/poster setup |
|
|
11:05 - 11:50
|
SESSION 1: Genomes, gene expression, DNA replication - Gert Veenstra/Luc Paillard |
|
| 11:05 - 11:20 |
› Reading and editing the genome of salamander Pleurodeles waltl reveals novel features of tetrapod regeneration - Ahmed Elewa, Karolinska Institute |
|
| 11:20 - 11:35 |
› Stage-specific histone modification profiles are shaped by mitotic activity - Daniil Pokrovsky, Ludwig Maximilian Universität, Biomedical Center |
|
| 11:35 - 11:50 |
› The transcriptome of a mucociliary epithelium provides novel insights into genome maturation - Alessandro Angerilli, Ludwig Maximilian Universität, Biomedical Center |
|
|
11:50 - 12:50
|
ROUND TABLE 1: Resource development: from collections and databases to genome editing (DIAPASON) |
|
|
12:50 - 14:15
|
Lunch (buffet)/poster setup |
|
|
14:15 - 15:15
|
SESSION 2 : Zootechnics and animal testing, amphibians and 3Rs - Luc Paillard/Christophe Heligon |
|
| 14:15 - 14:45 |
› The European Xenopus Resource Centre (EXRC) at the University of Portsmouth. - Colin Sharpe, European Xenopus Resource Centre |
|
| 14:45 - 15:15 |
› ReSAMA : A Network for Monitoring Health and Husbandry Practices in Aquatic Research Facilities. - Emmanuel LEGUAY, VETOFISH |
|
|
15:15 - 17:00
|
SESSION 3 : Evolution - Isabel Lopes/Nicolas Pollet |
|
| 15:15 - 15:45 |
› Genetic basis of sex determination in Xenopus tropicalis - Monica Bullejos, Universidad de Jaén |
|
| 15:45 - 16:15 |
› Prdm12 is an essential regulator of nociceptive sensory neuron differentiation - Eric Bellefroid, Université Libre de Bruxelles |
|
| 16:15 - 16:30 |
› The emergence of an exonic region with a peculiar splicing regulation - Luc paillard, Institut de Genetique et Developpement de Rennes |
|
| 16:29 - 16:45 |
› Regulatory remodeling in the allo-tetraploid frog Xenopus laevis - Gert Jan Veenstra, Radboud University |
|
| 16:45 - 17:00 |
› Taxonomic and functional resemblance between frog and mammalian gut microbiota. - Nicolas Pollet, Laboratoire Evolution, Génomes, Comportement, Ecologie |
|
|
17:00 - 17:30
|
Refreshment |
|
|
17:30 - 18:45
|
SESSION 5: Ecotoxicology and worldwide decline of amphibians - Isabel Lopes /David Du Pasquier |
|
| 17:30 - 18:00 |
› Protecting amphibians from risks associated with pesticides. Are we on the right path? - Manuel Ortiz-Santaliestra, Instituto de Investigación en Recursos Cinegéticos |
|
| 18:00 - 18:15 |
› Interactions of environmental stressors with the amphibian pathogen Saprolegnia australis - Sara Costa, Department of Biology & CESAM |
|
| 18:15 - 18:30 |
› Effects on thyroid signaling and early neurogenesis of pesticides amitrole and chlorpyrifos - Petra Spirhanzlova, Evolution des régulations endocriniennes_French national scientific research center/ National museum of natural history |
|
| 18:30 - 18:45 |
› Inter-laboratory OECD validation of the Xenopus Embryonic Thyroid Signalling Assay - David Du Pasquier, WatchFrog |
|
|
18:45 - 21:30
|
Dinner(buffet)/poster session |
|
| Time |
Event |
|
|
08:30 - 10:30
|
SESSION 6: Modeling human diseases in amphibians - Béatrice Durand/Kris Vleminckx |
|
| 08:30 - 09:00 |
› Arhinia: to Have or Not to Have a Nose - Bruno REVERSADE, Institute of Medical Biology |
|
| 09:00 - 09:30 |
› Models for hereditary renal malformations and cystic kidney diseases. - Soeren Lienkamp, Renal Division, Department of Medicine, University of Freiburg Medical Center |
|
| 09:30 - 09:45 |
› In-vivo negative-selection CRISPR/Cas9-based identification of novel drug targets in an Xenopus tropicalis tumor model - Thomas Naert, Department of Biomedical Molecular Biology and Cancer Research Institute Ghent, Ghent University, Belgium. |
|
| 09:45 - 10:00 |
› Polycystin-2 and FGF signaling are cooperatively required to set-up the left-right organizer during gastrulation in Xenopus - Philipp Vick, University of Hohenheim |
|
| 10:00 - 10:15 |
› A behavioral test to evaluate the funtional consequences in a Xenopus laevis model of inducible-demyelination and myelin repair. - Bernard Zalc, Universités UPMC Univ Paris 06, Inserm, CNRS, APHP, ICM- |
|
| 10:15 - 10:30 |
› Modeling human cancer and monogenetic disease in Xenopus tropicalis - Kris Vleminckx, Department of Biomedical Molecular Biology, Ghent University, Cancer Research Institute Ghent, Center for Medical Genetics Ghent, Ghent University |
|
|
10:30 - 10:50
|
Coffee break |
|
|
10:50 - 12:05
|
SESSION 4 : Cell signalling, pathways and receptors - Tomas Pieler / Kris Vleminckx |
|
| 10:50 - 11:20 |
› Chemical and mechanical cues control collective cell migration - Roberto Mayor, UCL |
|
| 11:20 - 11:35 |
› Using the frog to understand complex phenotypes in mucociliary development and disease - Peter Walentek, University of California, Berkeley, University Medical Centre Freiburg |
|
| 11:35 - 11:50 |
› Human Serotonin type 3 receptor subunit D (HT3D): A novel negative regulator of Wnt3a dependent signaling. - Axel Schweickert, University of Hohenheim, Institute for Zoology |
|
| 11:50 - 12:05 |
› Mixtures of xenobiotics found in human amniotic fluid modify embryonic thyroid hormone signalling and brain development - Jean-Baptiste Fini, Evolution des régulations endocriniennes_French national scientific research center/ National museum of natural history - Barbara Demeneix, Evolution des régulations endocriniennes_French national scientific research center/ National museum of natural history |
|
|
12:05 - 13:05
|
ROUND TABLE 2 : Imaging - Beatrice Durand |
|
|
13:05 - 14:30
|
Lunch (buffet) |
|
|
14:30 - 15:30
|
Keynote Talk \ John Gurdon - John Gurdon |
|
|
16:30 - 22:30
|
Social Event - Bus transportation to downtown Rennes, attraction (to be defined) and dinner. |
|
| Time |
Event |
|
|
08:30 - 10:30
|
SESSION 7: Development and organogenesis - Tomas Pieler/Karine Masse |
|
| 08:30 - 09:00 |
› Molecular Mechanism of Lung Development: Lessons from Xenopus - Aaron Zorn, Center for Stem Cell and Organoid Medicine, Divisions of Developmental Biology, Cincinnati Children's Hospital, and the Department of Pediatrics, College of Medicine University of Cincinnati |
|
| 09:00 - 09:30 |
› The Wnt receptor PTK7 is dynamically localized in migrating neural crest cells - Annette Borchers, Philipps-Universität Marburg |
|
| 09:30 - 10:00 |
› The role of Neil DNA glycosylases in neural crest development - Christof Niehrs, Institute of Molecular Biology |
|
| 10:00 - 10:15 |
› Breaking a dogma: CBFβ initiates the haematopoietic stem cell programme without obligatory binding to RUNX - Aldo Ciau-Uitz, MRC Molecular Haematology Unit |
|
| 10:15 - 10:30 |
› Molecular control of radial intercalation in a vertebrate epithelium - Alexandre CHUYEN, Institut de Biologie du Dévelopement Marseille |
|
|
10:30 - 10:50
|
Coffee break |
|
|
10:50 - 11:35
|
SESSION 7: Development and organogenesis - Tomas Pieler/Karine Masse |
|
| 10:50 - 11:05 |
› Mechanisms driving the temporal and selective induction of Ptf1a target genes - Sven Richts, Institute of Developmental Biochemistry, University Medical Center Goettingen, Center for Nano scale Microscopy and Molecular Physiology of the Brain (CNMPB) |
|
| 11:05 - 11:20 |
› XDSCR6 function during early embryonic development in vertebrates - Mafalda Loreti, Laboratory of Developmental Biology |
|
| 11:20 - 11:35 |
› Identification of Hnf1b and Fzd4 as Retinoic Acid-Induced Genes Responsible for Pancreas Specification - Maja Gere, Institute of Developmental Biology, University of Gottingen |
|
|
11:35 - 13:05
|
SESSION 8: Stem cells, regeneration - Gert Veenstra/Beatrice Durand |
|
| 11:35 - 12:05 |
› Müller glial cell-dependent regeneration of Xenopus retina - Muriel Perron, Neuroscience Institute of Paris-Sacaly |
|
| 12:05 - 12:35 |
› Exploring cardiac regeneration in Xenopus laevis - Laurent Coen, Evolution des régulations endocriniennes |
|
| 12:35 - 12:50 |
› A new brake on Wnt/ßCatenin activity in Spemann Organizer formation - Beatrice DURAND, Développement et évolution du système nerveux, Signalisation normale et pathologique de l'embryon aux thérapies innovante des cancers |
|
| 12:50 - 13:05 |
› Nitric oxide signaling during development, wound healing and regeneration - Radek Sindelka, Institute of Biotechnology, Czech Academy of Sciences |
|
|
13:05 - 13:35
|
Debriefing and organisational meeting (All Welcome) |
|
|
13:35 - 14:35
|
Lunch (buffet/take away)/ poster removal |
|
|
