|
Wednesday, June 28, 2017
| Time | Event | |
| 08:00 - 08:30 | Welcome and Registration - Welcome of participants and package distribution | |
| 08:30 - 08:45 | Few words of introduction | |
| 08:45 - 10:45 | SESSION 1: Genomes, gene expression, DNA replication (DIAPASON) - Gert Veenstra/Luc Paillard | |
| 08:45 - 09:15 | › Hedgehog-dependent E3-ligase Midline1 regulates ubiquitin-mediated proteasomal degradation of Pax6 - Thomas Hollemann, University of Halle-Wittenberg | |
| 09:15 - 09:45 | › Timing is everything: revisiting zygotic genome activation through the lens of time-resolved gene expression profiles - Mike Gilchrist, The Francis Crick Institute | |
| 09:45 - 10:15 | › Glucocorticoid effects on thyroid hormone gene regulation in Xenopus tropicalis tadpoles - LAURENT SACHS, Evolution of endocrines regulations | |
| 10:15 - 10:45 | › Identification of cis-regulatory elements in Xenopus neural crest formation - Grant Wheeler, University of East Anglia | |
| 10:45 - 11:05 | Coffee break/poster setup | |
| 11:05 - 11:50 | SESSION 1: Genomes, gene expression, DNA replication - Gert Veenstra/Luc Paillard | |
| 11:05 - 11:20 | › Reading and editing the genome of salamander Pleurodeles waltl reveals novel features of tetrapod regeneration - Ahmed Elewa, Karolinska Institute | |
| 11:20 - 11:35 | › Stage-specific histone modification profiles are shaped by mitotic activity - Daniil Pokrovsky, Ludwig Maximilian Universität, Biomedical Center | |
| 11:35 - 11:50 | › The transcriptome of a mucociliary epithelium provides novel insights into genome maturation - Alessandro Angerilli, Ludwig Maximilian Universität, Biomedical Center | |
| 11:50 - 12:50 | ROUND TABLE 1: Resource development: from collections and databases to genome editing (DIAPASON) | |
| 12:50 - 14:15 | Lunch (buffet)/poster setup | |
| 14:15 - 15:15 | SESSION 2 : Zootechnics and animal testing, amphibians and 3Rs - Luc Paillard/Christophe Heligon | |
| 14:15 - 14:45 | › The European Xenopus Resource Centre (EXRC) at the University of Portsmouth. - Colin Sharpe, European Xenopus Resource Centre | |
| 14:45 - 15:15 | › ReSAMA : A Network for Monitoring Health and Husbandry Practices in Aquatic Research Facilities. - Emmanuel LEGUAY, VETOFISH | |
| 15:15 - 17:00 | SESSION 3 : Evolution - Isabel Lopes/Nicolas Pollet | |
| 15:15 - 15:45 | › Genetic basis of sex determination in Xenopus tropicalis - Monica Bullejos, Universidad de Jaén | |
| 15:45 - 16:15 | › Prdm12 is an essential regulator of nociceptive sensory neuron differentiation - Eric Bellefroid, Université Libre de Bruxelles | |
| 16:15 - 16:30 | › The emergence of an exonic region with a peculiar splicing regulation - Luc paillard, Institut de Genetique et Developpement de Rennes | |
| 16:29 - 16:45 | › Regulatory remodeling in the allo-tetraploid frog Xenopus laevis - Gert Jan Veenstra, Radboud University | |
| 16:45 - 17:00 | › Taxonomic and functional resemblance between frog and mammalian gut microbiota. - Nicolas Pollet, Laboratoire Evolution, Génomes, Comportement, Ecologie | |
| 17:00 - 17:30 | Refreshment | |
| 17:30 - 18:45 | SESSION 5: Ecotoxicology and worldwide decline of amphibians - Isabel Lopes /David Du Pasquier | |
| 17:30 - 18:00 | › Protecting amphibians from risks associated with pesticides. Are we on the right path? - Manuel Ortiz-Santaliestra, Instituto de Investigación en Recursos Cinegéticos | |
| 18:00 - 18:15 | › Interactions of environmental stressors with the amphibian pathogen Saprolegnia australis - Sara Costa, Department of Biology & CESAM | |
| 18:15 - 18:30 | › Effects on thyroid signaling and early neurogenesis of pesticides amitrole and chlorpyrifos - Petra Spirhanzlova, Evolution des régulations endocriniennes_French national scientific research center/ National museum of natural history | |
| 18:30 - 18:45 | › Inter-laboratory OECD validation of the Xenopus Embryonic Thyroid Signalling Assay - David Du Pasquier, WatchFrog | |
| 18:45 - 21:30 | Dinner(buffet)/poster session |
Thursday, June 29, 2017
| Time | Event | |
| 08:30 - 10:30 | SESSION 6: Modeling human diseases in amphibians - Béatrice Durand/Kris Vleminckx | |
| 08:30 - 09:00 | › Arhinia: to Have or Not to Have a Nose - Bruno REVERSADE, Institute of Medical Biology | |
| 09:00 - 09:30 | › Models for hereditary renal malformations and cystic kidney diseases. - Soeren Lienkamp, Renal Division, Department of Medicine, University of Freiburg Medical Center | |
| 09:30 - 09:45 | › In-vivo negative-selection CRISPR/Cas9-based identification of novel drug targets in an Xenopus tropicalis tumor model - Thomas Naert, Department of Biomedical Molecular Biology and Cancer Research Institute Ghent, Ghent University, Belgium. | |
| 09:45 - 10:00 | › Polycystin-2 and FGF signaling are cooperatively required to set-up the left-right organizer during gastrulation in Xenopus - Philipp Vick, University of Hohenheim | |
| 10:00 - 10:15 | › A behavioral test to evaluate the funtional consequences in a Xenopus laevis model of inducible-demyelination and myelin repair. - Bernard Zalc, Universités UPMC Univ Paris 06, Inserm, CNRS, APHP, ICM- | |
| 10:15 - 10:30 | › Modeling human cancer and monogenetic disease in Xenopus tropicalis - Kris Vleminckx, Department of Biomedical Molecular Biology, Ghent University, Cancer Research Institute Ghent, Center for Medical Genetics Ghent, Ghent University | |
| 10:30 - 10:50 | Coffee break | |
| 10:50 - 12:05 | SESSION 4 : Cell signalling, pathways and receptors - Tomas Pieler / Kris Vleminckx | |
| 10:50 - 11:20 | › Chemical and mechanical cues control collective cell migration - Roberto Mayor, UCL | |
| 11:20 - 11:35 | › Using the frog to understand complex phenotypes in mucociliary development and disease - Peter Walentek, University of California, Berkeley, University Medical Centre Freiburg | |
| 11:35 - 11:50 | › Human Serotonin type 3 receptor subunit D (HT3D): A novel negative regulator of Wnt3a dependent signaling. - Axel Schweickert, University of Hohenheim, Institute for Zoology | |
| 11:50 - 12:05 | › Mixtures of xenobiotics found in human amniotic fluid modify embryonic thyroid hormone signalling and brain development - Jean-Baptiste Fini, Evolution des régulations endocriniennes_French national scientific research center/ National museum of natural history - Barbara Demeneix, Evolution des régulations endocriniennes_French national scientific research center/ National museum of natural history | |
| 12:05 - 13:05 | ROUND TABLE 2 : Imaging - Beatrice Durand | |
| 13:05 - 14:30 | Lunch (buffet) | |
| 14:30 - 15:30 | Keynote Talk \ John Gurdon - John Gurdon | |
| 16:30 - 22:30 | Social Event - Bus transportation to downtown Rennes, attraction (to be defined) and dinner. |
Friday, June 30, 2017
| Time | Event | |
| 08:30 - 10:30 | SESSION 7: Development and organogenesis - Tomas Pieler/Karine Masse | |
| 08:30 - 09:00 | › Molecular Mechanism of Lung Development: Lessons from Xenopus - Aaron Zorn, Center for Stem Cell and Organoid Medicine, Divisions of Developmental Biology, Cincinnati Children's Hospital, and the Department of Pediatrics, College of Medicine University of Cincinnati | |
| 09:00 - 09:30 | › The Wnt receptor PTK7 is dynamically localized in migrating neural crest cells - Annette Borchers, Philipps-Universität Marburg | |
| 09:30 - 10:00 | › The role of Neil DNA glycosylases in neural crest development - Christof Niehrs, Institute of Molecular Biology | |
| 10:00 - 10:15 | › Breaking a dogma: CBFβ initiates the haematopoietic stem cell programme without obligatory binding to RUNX - Aldo Ciau-Uitz, MRC Molecular Haematology Unit | |
| 10:15 - 10:30 | › Molecular control of radial intercalation in a vertebrate epithelium - Alexandre CHUYEN, Institut de Biologie du Dévelopement Marseille | |
| 10:30 - 10:50 | Coffee break | |
| 10:50 - 11:35 | SESSION 7: Development and organogenesis - Tomas Pieler/Karine Masse | |
| 10:50 - 11:05 | › Mechanisms driving the temporal and selective induction of Ptf1a target genes - Sven Richts, Institute of Developmental Biochemistry, University Medical Center Goettingen, Center for Nano scale Microscopy and Molecular Physiology of the Brain (CNMPB) | |
| 11:05 - 11:20 | › XDSCR6 function during early embryonic development in vertebrates - Mafalda Loreti, Laboratory of Developmental Biology | |
| 11:20 - 11:35 | › Identification of Hnf1b and Fzd4 as Retinoic Acid-Induced Genes Responsible for Pancreas Specification - Maja Gere, Institute of Developmental Biology, University of Gottingen | |
| 11:35 - 13:05 | SESSION 8: Stem cells, regeneration - Gert Veenstra/Beatrice Durand | |
| 11:35 - 12:05 | › Müller glial cell-dependent regeneration of Xenopus retina - Muriel Perron, Neuroscience Institute of Paris-Sacaly | |
| 12:05 - 12:35 | › Exploring cardiac regeneration in Xenopus laevis - Laurent Coen, Evolution des régulations endocriniennes | |
| 12:35 - 12:50 | › A new brake on Wnt/ßCatenin activity in Spemann Organizer formation - Beatrice DURAND, Développement et évolution du système nerveux, Signalisation normale et pathologique de l'embryon aux thérapies innovante des cancers | |
| 12:50 - 13:05 | › Nitric oxide signaling during development, wound healing and regeneration - Radek Sindelka, Institute of Biotechnology, Czech Academy of Sciences | |
| 13:05 - 13:35 | Debriefing and organisational meeting (All Welcome) | |
| 13:35 - 14:35 | Lunch (buffet/take away)/ poster removal |
|
|